by B. Robaire and P. Chan
List of Contributors
List of Contributors
What are the components of the male reproductive system?
CNS, pituitary, testis, epididymis, prostate, seminal vesicles, scrotum, penis
by K.P. Roberts
What is the relationship among the various endocrine components of the male reproductive system?
Hypothalamic-Pituitary-Testicular Axis, feedback loops
by R. Swerdloff
How are communication signals read in the male reproductive system?
Receptors for gonadotropins and androgens
by I. Huhtaniemi
What compounds mediate communication within the testis? Where and how are male-associated hormones produced?
Integration of the hypothalamus, pituitary and testis
by B.R. Zirkin
How is the synthesis of testosterone regulated?
by V. Papadopoulos
How are germ cells produced and what factors control their production?
by M. Nagano
What unique chromosomal events lead to the formation of a haploid male germ cell?
by M.A. Handel
How is the production of spermatozoa regulated?
Hormonal regulation of spermatogenesis: role of androgens and FSH
by R.I. McLachlan
Are there epigenetic events associated with male germ cell formation? What is the role of genomic imprinting in male germ cells?
Imprinting, DNA methylation
by J.M. Trasler
What does the epididymis do and how does it do it?
by B.T. Hinton
What is the prostate and what are its functions?
by G.S. Prins
How does semen analysis assist in understanding the reproductive status of the male?
by C. Wang
How is sperm chromatin structure assessed? What is the value of doing such assessments?
Range of methods that assess sperm chromatin quality
by B. Robaire
What is sperm banking? When and how is it (or should it be) used in humans? Animals?
Sperm banking, consequences of its use in animal and clinical practice
by S.A. Rothmann
How does the sperm make its way to the egg and how does fertilization take place?
Capacitation, acrosome exocytosis, steps of sperm-egg interaction, egg activation
by J.P. Evans and J.L. Bailey
What determines maleness?
Sex determination, testis formation and the development of the male phenotype
by D.W. Silversides and R.S. Viger
Are there specific genetic defects affecting the male reproductive tract? What are the underlying molecular mechanisms?
Turner’s and Klinefelter’s syndromes, genetic loci, GnRH/LH/FSH, steroid biosynthesis and androgen insensitivity
by T.R. Brown
Is there a trigger for puberty in the male? Should early or delayed puberty be treated? If so, how?
by T.M. Plant and S.F. Witchel
Clinical male infertility: Epidemiology and basic evaluation
by P. Chan
Why evaluate the infertile male in the era of ART?
Medical and surgical therapies for male infertility
by M. Goldstein
What are the assisted reproductive technologies for male infertility?
Indications for IVF/ICSI/IUI, Surgical sperm retrieval techniques
by P.N. Schlegel
Are there genetic factors associated with male infertility?
by D. Lamb
How can we assess the health outcomes in ART-conceived children?
Ethical issues in andrology
by T.J. Walsh and M.S. Croughan
How is male-factor subfertility minimized in companion and foodproducing animals?
by R.P. Amann
What should I know about artificial insemination (AI) of animals?
by R.P. Amann and D.L. Garner
Is there a decline in sperm counts in men?
by R.J. Sherins and G. Delbès
How do environmental cues affect male reproductive?
by W.W. Wright
What are the effects of environmental toxicants and/or endocrine disruptors on sperm function?
Chemical exposure effects on the male, reactive oxygen species and spermatozoa
by S.D. Perreault
Can spermatozoa be targets for drugs? If so, what are the consequences of such drug exposures? Is there a need for preconception counselling for men?
Drugs that affect sperm structure or function, male-mediated developmental toxicity, prevention, tests to detect damage to spermatozoa
by B.F. Hales and B. Robaire
Can we protect spermatogenesis against testicular insults?
Male reproductive toxicology
by M.L. Meistrich
What male contraceptives currently exist and what is the outlook for new male contraceptives?
by J.K. Amory and W.J. Bremner
What are the consequences of sexually transmitted infections on male reproduction?
by F. Ochsendorf
What types of testicular cancers occur in men? What is their prognosis? How effective are existing therapeutic approaches?
by N.E. Skakkebaek
How do erections occur? How common is erectile dysfunction, what is its etiology, and how do you evaluate men with this problem?
by P.M. Pierorazio and A.L. Burnett
How to treat erectile dysfunction?
by M.C. Raynor and W.J.G. Hellstrom
Is there an andropause, better known as Testosterone Deficiency Syndrome, and if so, what tissues are affected and how?
Fertility, androgen production and sensitivity, osteoporosis and sexual function in aging men
by A. Morales
Should there be hormone replacement therapy for aging men?
by J.L. Tenover
What is the importance of psychosocial issues, counseling and psychotherapy in andrology?
by N. Hunt and S. McHale
What is BPH?
by K.T. McVary
Are some men more susceptible to prostate cancer than others and why? What are the treatments and their effectiveness? What are the possibilities for improvements in therapy?
by D.J. Parekh and I.M. Thompson
What is the risk of testosterone therapy after prostate cancer?
by A. Morgentaler